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Enter Drug Name: (Trade  or Generic)



 
 Generic Name  Triprolidine HCl and pseudoephedrine HCl 
 Trade Name  Actifed 
 Manufacturer  GlaxoWellcome 
 Risk Category    
C
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.


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 Indication  

  • Antihistamine, sympathomimetic to relieve symptomes of upper respiratory tract disorders.
 Fetal Risk  

  • No fetal adverse effects for triprolidine in animals but no well - controlled human data, suggested possible association with cardiovascular defects in 1st trimester exposure.
  • No adequate data for pseudoephedrine but suggested possible association with gastroschisis in 1st trimester exposure and for sympathomimetic drugs in general, they are teratogenic in animals possibly associated with minor malformations, club foot and inguinal hernias in human pregnancy.
 Breast Feeding  

  • Both drugs excreted into milk safe in breast feeding.
 Other Trade Names  
 


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Last complete update: 10/05/2006