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- Teratogenic
in some animals.
- No well controlled human data but suggested possible associaiton between first trimester exposure to the drug and congenital anomalies including: cardiovascular, limb, renal defects, cleft palate, adrenal hypoplasia, diaphragmatic hernia, defective abdominal muscles and exencephaly.
- Causes withdrawal symptoms and urinary retention in neonates exposed in utero.
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