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Enter Drug Name: (Trade  or Generic)



 
 Generic Name  Lorazepam 
 Trade Name  Lorazepam intensol 
 Manufacturer   
 Risk Category    
D
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).


 Place (not click) your mouse cursor over the bold words in the text below to receive description
 Indication  

  • Benzodiazepine.
  • Sedative-hypnotic, antianxiety, anticonvulsant, antipanic.
 Fetal Risk  

  • Fetotoxic in animals causing fetal resorption and increased fetal loss.
  • Crosses human placenta. No well-controlled human data but benzodiazepines are associated with increased risk of congenital anomalies if used in 1st trimester. Chronic use of benzodiazepines throughout pregnancy is associated with neonatal withdrawal and if used in last weeks of pregnancy they can cause neonatal CNS depression.
 Breast Feeding  

  • Excreted into milk and potential to cause sedation, feeding difficulties and weight loss in nursing infants.
 Other Trade Names  
 


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Last complete update: 10/05/2006