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Enter Drug Name: (Trade  or Generic)



 
 Generic Name  Danazol 
 Trade Name  Cyclomen 
 Manufacturer   
 Risk Category    
X
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
  • Studies in animals and/or humans have demonstrated fetal abnormalities.
  • Fetal risk involved in use of drug, clearly outweighs potential benefit.
  • Contraindicated in women who are or may become pregnant. Don’t use.


 Place (not click) your mouse cursor over the bold words in the text below to receive description
 Indication  

  • Synthetic androgen for treatment of endometriosis, fibrocystic breast disease and hereditary angioedema.
 Fetal Risk  

  • Crosses the placenta in animals.
  • Teratogenic in human causing virilization with ambigeous genitalia of female fetuses exposed to the drug in utero, without major birth defects.
  • No evidence of virilization when danazol was stopped before conception or before the eighth week of embryogenesis.
  • Virilization of the behavior of young females exposed in utero to danazol has been reported.
 Breast Feeding  

  • Drug contraindicated in breast-feeding women.
 Other Trade Names  
 


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Last complete update: 10/05/2006