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Enter Drug Name: (Trade  or Generic)



 
 Generic Name  Tacrolimus 
 Trade Name  Tacrolimus 
 Manufacturer   
 Risk Category    
C
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.


 Place (not click) your mouse cursor over the bold words in the text below to receive description
 Indication  

  • Immunosuppressant for prevention of graft rejection.
 Fetal Risk  

  • fetotoxic in animals causing increased late fetal loss and decreased live birth rate.
  • Crosses human placenta.
  • No adequate human studies, but reported to cause preterm delivery, intrauterine growth retardation (single case), hyperkalemia and reversible renal impairment in the neonates.
 Breast Feeding  

  • Excreted into milk.
  • Breastfeeding should be discontinued during therapy.
 Other Trade Names  
 


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Last complete update: 10/05/2006